RRSH Logo with Event Text

10th International Meeting on Rapid Responses to Steroid Hormones

RRSH 2016
November 2th - 5th, 2016
Richmond, Virginia
VCU Monroe Park Campus

The RRSH Conference will be held at VCU’s College of Engineering West Hall, Auditorium/Room 101 (bottom floor). A 35 room block has been set up at Richmond’s boutique hotel The Quirk. Click here to book a room at The Quirk utilizing RRSH pricing (same pricing available on shoulder dates, please call Hannah Wallingsford at 804-644-3404 to arrange shoulder date requests). The RRSH Banquet dinner will be held at the Historic Bolling Haxall House

RRSH will happen during Richmond’s ‘First Friday’ events - a monthly happening, equaling “a year round art walk, featuring the shops, galleries, restaurants, and organizations in The Arts District of Richmond, Virginia.” Your hotel is centrally located to all the action. While expanding your scientific mind through the RRSH conference, take this opportunity to explore Richmond’s eclectic and artistic culture as well.

Click Here to See Photos from the RRSH 2016 Event


Wednesday, November 2nd, 2016

Quirk Hotel

  • 5:00 PM - 7:00 PM: Registration and Welcome Reception

Thursday, November 3rd, 2016

VCU Monroe Park Campus
College of Engineering

  • 7:30 AM - 8:30 AM: Continental Breakfast
  • 8:30 AM - 8:45 AM: Welcome - Deans Barbara Boyan and Jerry Strauss
  • 8:45 AM - 10:15 AM: Estrogen Receptor Signaling: Jack Caldwell, Chair
    - Gustav Jirikowski: Estrogen Receptor Isoforms in Neuronal PC12 Cell 
    - Jack Caldwell: Sex hormone binding globulin’s role in estradiol internalization 
    - Cheryl Watson: Xenoestrogen Interference with nongenomic Signaling Actions of Physiological Estrogens in Prostate and Pituitary Cancer Cells
  • 10:15 AM - 10:30 AM: Coffee/snack break
  • 10:30 AM - 12:00 PM: Membrane Mediated Crosstalk: Cheryl Watson, Chair
    - Troy Roepke: Membrane-initiated estrogen signaling in hypothalamic CRH neurons is mediated by a Gq-coupled mER‌
    - Barbara Boyan: Role of caveolae in mediating Pdia3-VDR crosstalk
    - John Meitzen: Estrogen receptor function, palmitoylation, and mGluR‌
  • 12:00 PM - 1:00 PM: Lunch on your own
  • 1:00 PM - 2:30 PM: Glucocorticoids: John Cidlowski, Chair
    - Jeff Tasker: Nuclear trafficking of the glucocorticoid receptor induced by a membrane receptor mechanism
    - John Cidlowski: A corneal view of glucocorticoid action in the eye
    - Short Talk: Mark Shui-Yu Liu: DHEA Inhibits Intracellular Calcium Elevation and NETosis by MSU Crystals
  • 2:30 PM - 2:45 PM: Coffee/snack break
  • 2:45 PM - 4:30 PM: Alternative Receptors: Martin Wehling, Chair 
    - Martin Wehling: Rapid actions of aldosterone: receptors in the limelight
    - Eric Prossnitz: Understanding GPER's functions in physiology and disease
    - Patricia Elizalde: ErbB-2 and breast cancer
Travel by shuttles, walk, or car to Bolling Haxall House

  • 5:30 PM - 6:30 PM: Cocktail hour at Bolling Haxall House
  • 6:30 PM - 8:00 PM: Dinner banquet

Friday, November 4th, 2016

VCU Monroe Park Campus
College of Engineering

  • 7:30 AM - 8:30 AM: Continental Breakfast
  • 8:30 AM - 10:00 AM: Membrane Structure Function Relationships: Paul Davis, Chair
    - Gustav Jirikowski: The Rat Vomeronasal Organ is a Vitamin D Target
    - Paul Davis: Role of Integrin αvβ3 in Nongenomic Actions of Thyroid Hormone, Dihydrotestosterone and Resveratrol
    - Pin Tsun Kuo: In Human Peripheral T Cells Estrogen Receptor Antagonists Inhibit the Rapid Intracellular Calcium Elevation, but not the Immunosuppression Brought about by Bisphenol A
  • 10:00 AM - 10:15 AM: Coffee/snack break
  • 10:15 AM - 11:45 AM: Rapid Fire TalksJerry Strauss, Chair
    - Luca Franco Castelnovo: Expression of Membrane Progesterone Receptors (mPRs) in Rat Peripheral Glial Cell Membranes and their Potential Role in Myelination
    - Kevin Sinchak: Tamoxifen and ICI 182,720 Rapid Facilitate Sexual Receptivity via Activation of G Protein-coupled Estrogen Receptor 1 (GPER) in Orphanin FQ (nociception) Neurons
    - John Ryan: PDIA3 and mast cell function
    - Roberto De Luca: Thyroxine (T4) and negative effective factor (Nef) crosstalk: a new model for thyroid dysfunctions during human immunodeficiency virus (HIV) infection
    - Jerry Strauss: Anti-aniogenic and Pro-angiogenic Estrogen Metabolites
  • 11:45 AM - 1:15 PM: Lunch on your own
  • 1:15 PM - 2:45 PM: Clinical Applications: Eileen Chien, Chair
    - Matthias Barton: Clinical significance of GPER
    - Eileen Chien: The non-genomic effects on immunosuppression in human T-cells brought about by progesterone probably occur via TRPC3
    - Sandra Incerpi: Short-term effects of thyroid hormones in THP-1 monocytes
  • 2:45 PM - 3:15 PM: Coffee and networking
  • 3:15 PM - 4:45 PM: Androgens and Progesterone: Peter Thomas, Chair
    - Peter Thomas: Rapid zinc signaling mediated by testosterone through the novel membrane androgen receptor, ZIP9, coupled to a G protein
    - Vasiliki Pelekanou: Estrogen receptor profiling in Non-small Cell Lung Cancer (NSCLC)
    - Yefei Pang: Role of membrane progesterone receptor alpha (mPRa) in progesterone regulation of human vascular smooth muscle relaxation
  • 4:45 PM - 6:30 PM: Poster Session Reception (Please refer to the end of the schedule section for the full list)
  • Dinner on your own at the First Friday Art Scene on Broad Street

Saturday, November 5th, 2016

VCU Monroe Park Campus
College of Engineering

  • 7:30 AM - 8:00 AM: Continental Breakfast
  • 8:00 AM - 9:30 AM: Rapid Actions and Cancer II: Sarah Spiegel, Chair
    - Zvi Schwartz: Laryngeal cancer metastasis is promoted by 17β-estradiol through membrane-associated ERα36, similar to other estrogen-sensitive cancers
    - Sarah Spiegel: Role of sphingosine-1-phosphate in estrogen receptor signaling in breast cancer
    - Short Talk: D. Joshua Cohen: Estrogen Stimulates Osteolysis by ERα66 Negative, ERα36 Positive MDA MB-231 Breast Cancer Cells in Athymic Nude Mice
  • 9:30 AM - 9:45 AM: Coffee/snack break
  • 9:45 AM - 10:45 AM: Mechanisms of Action: Gustav Jirikowski, Chair
    - Jens Pedersen: Thyroid hormones form relatively stable radical intermediates under physiological conditions‌
    - Short Talk 1: Anjali Verma: 24R,25(OH)2D3 regulation of tumorigenesis is ERα-‌dependent in breast cancer cells‌
  • 10:45 AM - 11:00 AM: Closing - Deans Barbara Boyan and Jerry Strauss
  • 11:00 AM: Boxed lunches available to those that requested

Poster Presentations

  • Mark Shui-Yu Liu: DHEA inhibits intracellular calcium elevation and NETosis by MSU crystals
  • Faegheh Ghanbari: Structural and functional characterization of a novel endogenous steroid, estradienolone (ED) in human pregnancy urine
  • Kayla Scott: 24R,25(OH)2D3 reduces articular cartilage degradation in a rat osteoarthritis model
  • Melissa Maczis: Estrogen receptor alpha splice variant ERa36 regulates sphingosine kinase 1/spingosine-1-phosphate axis in triple negative breast cancer
  • Sharon Hyzy: Role of genomic v. non-genomic 1α,25(OH)2D3 signaling in allergically-stimulated cells
  • Jack D. Caldwell: Confocal microscopic co-localization of sex hormone binding globulin and estradiol receptor-β in PC12 cells.
  • Gustav Jirikowski: Estrogen receptor isoforms in neuronal PC12 cell cultures
  • Mandi Botes: The estrone derivative EE-15-one induces rapid anoikis in ER positive and TNBC cell lines in vitro
  • Marie-Pierre Moisan: Corticosteroid binding globulin deficiency and glucocorticoid-dependent memory processes